Patient information

How ACTIfit Works

ACTIfit is a resilient, flexible, highly porous, biodegradable and biocompatible synthetic scaffold. It is a honeycomb like structure, through which blood vessels can rapidly grow. The blood transports cartilage repair cells and other nutrients that initiate the growth of new meniscus-like tissue.

Benefits of ACTIfit

With ACTIfit, patients can enjoy a reduction of pain through a single surgical procedure. Over time, the new meniscus-like tissue grown through ACTIfit will increase patients’ chances of a future free from pain, loss of mobility, cartilage damage, and further degeneration that normally leads to osteoarthritis and total knee replacement.

The pre-clinical and clinical studies show the new polymer material to be safe and effective. It has the ability to promote robust, cellular in-growth of new meniscus-like tissue. Human clinical trials have shown significant pain reduction and very promising results with regard to quality of life and a return to pre-injury activity levels.

Our mission with ACTIfit is to reduce your meniscal pain and return you to a quality of life that is the same, or similar, to that enjoyed before their meniscus tear.

How ACTIfit Works
Meniscus defect.
Tissue regeneration through vascular and cellular in-growth into ACTIfit scaffold.
Regenerated tissue integrated with host tissue.
About ACTIfit

ACTIfit was developed with several world leading orthopedic sports/medicine surgeons. ACTIfit is:

  • A patented unique polymer
  • The first biodegradable, synthetic meniscal scaffold
  • Designed to help repair meniscal tears
  • Safe, tough and extremely easy to handle in surgery

A meniscus tear is normally repaired by the removal of the damaged tissue via a partial meniscectomy. Sometimes effective in the short term; however, it only gives temporary pain relief. In many cases the pain returns in time due to meniscal tissue loss and impaired/decreased cushioning function. Longer period there is overwhelming evidence that degenerative changes occur, which, if left untreated, leads to joint narrowing, articular cartilage damage and the onset of osteoarthritis - eventually a total knee replacement.

ACTIFIT BY NUMBERS

25

Clinical Studies

30

+

Countries

4,000

+

Patients Treated

1

FDA Breakthrough Designation