CartiONE is a single surgery, Autologous Chondrocyte Implantation (ACI) procedure providing surgeons with a cell combination of the patient’s own freshly isolated cartilage and bone marrow cells. Results from Orteq’s original cell single-stage ACI procedure using the osteochondral Instruct Scaffold have been published in the American Journal of Sports Medicine.
CartiONE offers the same ACI treatment cell fresh chondrocyte bone marrow cell combination but:
For further information on Clinical Studies or on the technology please contact Orteq at firstname.lastname@example.org
Dr Konrad Słynarski
Słynarski Knee Clinic
Prof Peter Verdonk,
Orthoca Orthopedic Center
Prof Martyn Snow
Prof Stefan Marlovits
Dr Emmanuel Papacostas
Aspeter Clinic Qatar
Konrad Słynarski, MD, PhD, Willem Cornelis de Jong, PhD, Martyn Snow, FRCS, Jeanine Anna Alphonse Hendriks, PhD, Clayton Ellis Wilson, PhD, and Peter Verdonk, MD, PhD.
Investigation performed at Ghent University Hospital, Ghent, Belgium; The Royal Orthopaedic Hospital NHS Foundation Trust, Birmingham, UK; The Center of Sports Medicine, Warsaw, Poland; AVIMED Hospital, Katowice, Poland; NSZOZ Endomedical, Poznan, Poland; and Dr Jan Biziel University Hospital No. 2, Bydgoszcz, Poland.
The first Instruct/CartiONE single-stage clinical study was recently published in the American Journal of Sports Medicine in April 2020.
The INSTRUCT for Repair of Knee Cartilage Defects Study (ClinicalTrials.gov, NCT01041885) was a prospective, single-arm, multicenter, multinational study conducted at 6 European sites in Belgium, the UK, and Poland. It included 40 patients with symptomatic knee cartilage lesions treated with freshly isolated autologous chondrocytes combined with bone marrow-derived cells and delivered in a biodegradable load-bearing scaffold.
The treatment is a cost-effective single-stage ACI alternative to the traditional two-stage autologous chondrocyte implantation (ACI) options.